Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

FORMULATION AND EVALUATION OF MEDICATED CHEWING GUM OF CHLORPHENIRAMINE MALEATE BY MELTING METHOD

Koppula Rajitha* and Yamsani Madhusudhan Rao

ABSTRACT

Medicated chewing gums of chlorpheniramine maleate were prepared by melting process using different concentrations of synthetic gum base and plasticizers like glycerol and castor oil. The prepared chewing gums are evaluated for different parameters like appearance, stickiness, weight variation, drug content, hardness, thickness, in vitro drug release. In vitro drug release was performed by modified dissolution apparatus. It was seen that in formulations F4-F9 drug release was decreased compared to formulation series F1-F3. It was observed that as the concentration of synthetic gum base increases drug release was decreases. The formulation F3 shows maximum drug release of 90.89% in 30 minutes compared to all other formulations. So that melting method is suitable to prepare medicated chewing gums of chlorpheniramine with optimum concentration of plasticizer and synthetic gum base.

Keywords: Medicated chewing gums, glycerin, castor oil, synthetic gum base, melting method.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More