Abstract

EVALUATION OF IN VITRO HEMOLYTIC ACTIVITY OF DIFFERENT PARTS OF ABUTILON INDICUM (LINN.)

S. Shobana and R. Vidhya*

ABSTRACT

In the present study different parts of (Leaf, Stem, flower and Pod) acetone extracts of Abutilon indicum (L.) were determine for the analysis of pytochemical and in vitro hemolytic activities. The evaluation of in vitro hemolytic activity was screened by using hypotonic induced saline and heat induced hemolysis method. The result of present study, maximum bioactive phytocompounds were present in the flower extract compared to leaf, stem and pod of A. indicum. The acetone extract of A. indicum leaf showed minimum hemolysis against human erythrocytes. In heat induced method, the mild RBC lysis was observed in acetone extract of leaf, when compared to other parts of A. indicum. In future to determine the active phytocompounds present in A. indicum, that to design the pharmaceutical drugs for the treatment of various diseases and less toxicity.

Keywords: In vitro, Hemolytic activity, Heat induced hemolysis, Abutilon indicum, Erythrocyte, acetone extract.