Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.



Hassanien Sagban Taghi, Alaa A. Abdul Rasool* and Yehia Ismail Khalil


Cyclodextrin-based nanosponges are hyper cross-linked polymeric networks formed by cyclodextrins and cyclodextrin derivatives; they obtained by reacting cyclodextrin with cross-linker agents such as (carbonyl diimidazole, organic carbonates, and carboxylic dianhydride) and have many applications as drug delivery systems for pollutants removal in environmental issues and industrial fields. Several β-CD, sulfobutylether-β-CD and hydroxypropyl-β-CD nanosponges were prepared using suitable substance as cross-linker. They have been used to increase the solubility and stability of poorly soluble pharmacological active substances, as they combine the complex forming properties of CDs and properties of polymers. The cyclodextrin capacity to form inclusion complexes is enhanced when the CD molecules form aggregates or cross-linked together with other compounds (crosslinker), we have synthesized cyclodextrin based nanosponges (from HP-b-cyclodextrin). The complexing properties of the nanosponges were investigated against tenoxicam (non-steroidal anti-inflammatory drug, practically insoluble in water) and compared with native HP-b-CD monomer. Solubility studies were performed according to the method reported by Higuchi and Connors and the phase solubility diagrams were plotted and used to calculate the values of apparent stability constant and complexation efficiency. The results showed the significant enhancement in aqueous solubility of tenoxicam by 3.17 folds higher.

Keywords: Tenoxicam, Beta cyclodextrin nanosponge, Solubilization enhancement, Complexation efficiency.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More