Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

FIVE SPECTROPHOTOMETRIC METHODS FOR DETERMINATION OF ETILEFRINE HCl IN BINARY MIXTURE WITH CHLORPHENIRAMINE

Khalid Abdel-Salam M. Attia, Nasr M. El-Abasawy and Ahmed M. Abdelraoof*

ABSTRACT

Five Simple, rapid, sensitive, accurate and precise stability-indicating spectrophotometric methods were developed for the determination of Etilefrine hydrochloride (ETF) in bulk powder and in pharmaceutical preparation. Method (A) Ratio derivative method (1DD), Method (B) Ratio difference method, Method (C) Mean centering method, Method (D) Dual wavelength method and Method (E) Area under the curve (AUC). These methods were used for the determination of Etilefrine hydrochloride in binary mixture with (chlorophenermine maleate) (CPM). These methods were validated and successfully applied to the determination of Balkis ® capsule with an average percent recovery ± RSD% of 100.26± 0.622 for method (A), 99.73 ± 0.583 for method (B), 99.15 ± 0.670 for method (C), 99.63 ± 0.862 for method (D) and 99.41 ± 1.225 for method (E). The obtained results were statistically compared with those of the reported method by applying t-test and Ftest at 95% confidence level and no significant difference was observed regarding accuracy and precision.

Keywords: Etilefrine, Ratio derivative, Ratio difference, Mean centering, Dual wavelength, Area under curve.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More