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EFFECT OF AQUEOUS EXTRACT OF ALLANBLACKIA FLORIBUNDA (OLIVER) STEM BARK ON SEXUAL BEHAVIOUR IN ADULT MALE RATS
*Kada Sanda Antoine1, Mieugue Pierre2, Dzeufiet Djomeni Paul Désiré1, Faleu Nya
1Laboratory of Animal Physiology, Department of Animal Biology and Physiology, University of Yaounde I, P.O BOX 812, Yaounde, Cameroon. ABSTRACT The use of natural products for the treatment of sexual disorders is under current investigation. People in central region of Cameroon have used, for many years, Allanblackia floribunda (Oliver), because of their belief that it improves fertility and sexual desire. The phytochemical constituents of aqueous extract of Allanblackia floribunda (Oliver) stem bark and its effect on male rat sexual behaviour were evaluated for 8 days. Phytochemical screening revealed the presence of alkaloids, saponins, triterpenoids, phenols, polyoses, tannins and flavonoids. Administration of the extract at the dose of 150 mg/kg body weight resulted in the significant increase (p ˂ 0.001) of mount frequency, intromission frequency, ejaculatory latency, penile licking frequency, computed indices of sexual behaviour and wiring-touch frequency whereas the mount latency, intromission latency and post-ejaculatory interval were significantly decreased (p ˂ 0.001) throughout the experimental period. The 300 \ mg/kg body weight of the extract showed few activities on sexual parameters monitored throughout the experimental period and on others parameters. This dose showed contrasting pattern to the lower dose. The present data show the stimulating potential of Allanblackia floribunda aqueous extract on sexual desire and potency of male rats. The aqueous extract of Allanblackia floribunda stem bark at the dose 150 mg/kg body weight may be used in the management of disorders of desire/libido, premature ejaculation and erectile dysfunction in males. Keywords: Allanblackia floribunda, sexual behaviour, libido, erectile dysfunction, sexual motivation, premature ejaculation. [Full Text Article] |