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Abstract

SYNTHESIS AND BIOLOGICAL EVALUTION OF 3-((E)-2,3- DIHYDRO-2-ARYL BENZO[B][1,4]THIAZEPIN-4-YL)-4-HYDROXY-1- METHYLQUINOLIN-2(1H)-ONE.

Lanka Annapurna* and Pochampally Jalapathi.

ABSTRACT

Simple and convient procedure have been developing for the synthesis of 3-((E)-2,3-dihydro-2-aryl benzo[b][1,4]thiazepin-4-yl)-4- hydroxy-1-methylquinolin-2(1H)-one 4(a-e) by condensation reaction between 2-amino thiophenol and chalcones 3(a-e) using benzyl tri ethyl ammonium chloride.in ethanol.

Keywords: BTEAC, 2-amino thiophenol, chalcones, 1,5- benzothiazepines.


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