Abstract

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL INVESTIGATIONS OF SOME NEW Mn(II) COMPLEXES WITH MIXED AZINES

Sunita Choudhary, S. Varshney and A. K. Varshney*

ABSTRACT

A new series of Mn(II) complexes were synthesized by the reaction of manganese(II) acetate with mixed azines using methanol as a reaction medium. Mixed azines used in these studies have been prepared by the condensation of hydrazine hydrate and suitable carbonyls in ethanol. The prepared complexes were isolated as solid products and characterized by elemental analysis, spectral studies and conductivity measurement. On the basis of elemental analysis the metal complexes are suggested to obtain in 1:2 molar ratios (metal- ligand). Monomeric nature of these complexes has been confirmed on the basis of their molecular weight determination. On the basis of spectral studies, a six coordinate distorted octahedral geometry for all of these complexes have been assigned. The biological activities of mixed azines and their metal complexes with different concentration have been screened invitro against some bacterial and fungal strain to assess their growth inhibitory potency. The metal complexes were shown to posses more antibacterial and antifungal activities than the free mixed azine ligands.

Keywords: Mn(II) complexes, Mixed azines, Spectroscopic characterization, Biological studies