Abstract

OVER REVIEW OF MICROSPONGES – ADVANCED NOVEL TECHNOLOGY

S. Dasthagiri*, P. Jagadeesh, S. B. Thirumallesh Naik and G. Nethravani

ABSTRACT

To control the delivery rate of active agents to a predetermined site in human body has been one of the biggest challenges faced by scientists. MDS is a unique technology for the controlled release of topical agents, also use for oral as well as biopharmaceuticals (peptides, proteins and DNS-based therapeutics) drug release. Microsponges are highly porous micro sized particles with a unique ability for entrapping active pharmaceutical ingredients and consist of macro porous beads, topically 60-25 microns in a diameter loaded with active ingredient. it active ingredients on a time mode and also in response to other stimuli and MDS technology is being used currently in cosmetics ,over-the – counter skin care, sunscreens and prescription products. Microsponges possess the versatility to load a wide range of active providing the benefits of enhanced product efficacy, mildness, tolerability and extended over to a wide range of skin therapies. Microsponges delivery system can be incorporated into conventional dosage forms such as creams, lotions, gels, ointments, powder and share a broad package of benefits. This review covers the advantages of microsponges, their formulation and applications in field.

Keywords: Microsponges, SEM,TEM, Dissolution Studies.