Abstract

BISMUTH (III) BROMIDE-CATALYZED AN EFFICIENT PROTOCOL FOR THE SYNTHESIS OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONES

K. R. Gopinath, H. S. Shekar, K. J. Rajendraprasad, H. Nagabhushana and Manjula Krishnappa*

ABSTRACT

The new protocol has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones using Bismuth(III)bromide as a catalyst, using two component intermolecular one pot condensation of anthranilamide with various aryl aldehydes. The reaction proceeded in short period of time with high yields using low toxicity bismuth compound.

Keywords: Bismuth (III) bromide (BiBr3), 2,3-dihydroquinazolin-4(1H)-ones (2,3-DHQs), anthranilamide and aryl aldehydes.