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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.485

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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Abstract

EFFECT OF ALCHOLIC EXTRACT OF PORTULACA OLERACEA LINN FROM PULWA DISTRICT OF KASHMIR VALLEY ON ALLOXAN- INDUCED DIABETIC RATS

Prince Ahad Mir, Neha Sharma and G. N. Bader*

ABSTRACT

Portulaca oleracea Linn belongs to the family Portulacaceae. Traditionally it is used in conditions of diarrhea, dysentery, leprosy, ulcers, asthma, piles, to reduce small tumors and inflammations. The aim of this work was to study the effect of ethanolic extract of this herb on pancreas in the alloxan induced diabetic rats and to see whether there exists any geographical variation as per its pharmacological effect is concerned. The alcoholic extract of Portulaca oleracea Linn from Pulwama district of Kashmir valley at the dose level of 400 mg/kg b.w showed the maximum protection against degeneration of acinar cells caused by alloxan (150 mg/kg b.w). Glibenclamide was used as standard. The extract showed dose dependent protection which was revealed by hematoxylin and eosin stained pancreatic tissue.

Keywords: Pancreas, Portulaca oleracea, diabetes mellitus, albino rats.

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