Abstract

ANTHELMINTIC POTENTIALS OF LEAF EXTRACTS OF MEDICINAL PLANTS; A BRIEF REVIEW

Chaluvaraju K C*, Khajaphir Makrabbi, Zaranappa, Naveenkumar K L

ABSTRACT

Helminthiasis, also known as helminth infection or worm infection is one of the most prevalent disease seen in developed and developing contries. The synthetic drugs are used to cure the desease but due to their toxicity and adverse effects use of herbal remedies predominates. The present study is mainly focused on the various leaf extracts which were used as herbal anthelmintics their method of collection, extraction of phytochemicals, screening-evaluation of in-vitro, in-vivo anthelmintic activity. In majority of cases the in-vitro anthelmintic activity was performed on indian adult earthworm pheritima postuma and methanolic, ethanolic, aqueous extracts have showed activity in a dose depended manner, more potent than the reference standards. From the above studies it can be concluded that leaves could be categorized under anthelmintic herbal drugs and become a potent key ingredient of such herbal formulation.

Keywords: Helminthiasis, Pheritima postuma, Ascardia galli, Anthelmintics, phytoconstituents, Herbal leaves.