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  • OCTOBER 2020 Issue has been successfully launched on 1 October 2020.

Abstract

DRUG AND MULTI-DRUG RESISTANT TUBERCULOSIS: A COMPREHENSIVE REVIEW ON MANAGEMENT

Rajendra Prasad*, Nikhil Gupta, Viswesvaran Balasubramanian, Abhijeet Singh

ABSTRACT

Drug resistant tuberculosis, a phenomenon observed since the early days of introduction of anti-tubercular chemotherapy, is becoming an area of growing concern. It is posing threat to global efforts of tuberculosis control. A prompt recognition of mono-, poly- and multidrug-resistance is imperative for prognosis and formulating better management strategies. The prevalence of multi-drug resistant tuberculosis, mirrors the functional state and efficacy of tuberculosis control programme and realistic attitude of the community towards implementation of such programmes. The management of drug resistant tuberculosis is difficult, expensive, challenging and quite often leads to treatment failure. To avoid further transmission, a comprehensive approach for rapid detection, proper treatment and effective public health measures must be ensured. It must also be emphasized that even optimal treatment of MDR-TB will not alone curb the epidemic. Efforts must be focused on the effective use of first-line drugs in every new case so as to prevent the ultimate emergence of MDR-TB.

Keywords: multi-drug resistant tuberculosis, mirrors the functional state and efficacy.


[Full Text Article]

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