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Elahe Elhami* and Kiran Nagaraju


Background: High blood pressure, or hypertension, is a major factor in the development of kidney problems in people with diabetes. Both a family history of hypertension and the presence of hypertension appear to increase chances of developing kidney disease. Objective: To determine the drug utilization evaluation of antihypertensive drugs in diabetic patients with CKD in a department of Nephrology, KIM’s hospital, Bangalore. Method: Retrospective observational study was conducted from March 2010 to August 2015 in 120 renal failure patient admitted to General Medicine at KIMS hospital, Bangalore. Information from the case sheets was retrieved into a well designed data collection form from diabetic patients with CKD. Results: Out of 120 diabetic patients with CKD, 70 (58.33) were male and 50 (41.66%) were females with mean age of 53.10±11.27 years. In the enrolled patients, we found that a total of 30patients (36%) were on monotherapy, 60 (50%) on two drug therapy, 24 (20%) on three drug therapy. The most common drug prescribed was ACE follow by diuretics drugs. About 66.66% of the prescribed drugs where from Essential Drug List (EDL) 2015. In our study only 34.21% patients were prescribed generic names. Conclusion: about (39.78%) of the patients are been prescribed with ACEI’s in accordance with the JNC _7 guideline. and most of drugs were found to be rational and it also shows the management of hypertension in DM patients with CKD needs combination therapy.

Keywords: Antihypertensive drug, CKD, drug utilization evaluation, JNC _7.

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