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Abstract

ANTHELMINTIC ACTIVITY OF HELICTERES ISORA LINN. FRUITS EXTRACT.

Darshan Vinod Shah*, Shyale Somshekhar S., Selveya Subhash Soloman

ABSTRACT

The present research programme was aimed to investigate the anthelmintic activity of the aqueous extract of Helicteres isora fruit against adult Indian earthworm Pheritimaposthuma, Various concentrations (50 and 100 mg/ml) of aqueous extract evaluated for anthelmintic activity by recording the time required for paralysis and death of worms. Albendazole (20mg/ml) was used as standard. Result indicates aqueous extract of Helicteres isora fruit significantly (p<0.01) exhibited anthelmintic activity in dose dependent manner when compared with standard. The aqueous extract of Helicteres isora fruit have been confirmed to display anthelmintic activity. Further studies are under progress to confirm the possible chemical constituents responsible for activity.

Keywords: Anthelmintic, Helicteres isora linn, Earth worms, Paralysis.


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