Abstract

MOUTH DISSOLVING TABLET: REVIEW

Preeti Pokhariya*, G Ganarajan and Preeti Kothiyal

ABSTRACT

Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. Fast- or mouth dissolving tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Fast dissolving Tablets are disintegrating and/or dissolve rapidly in the saliva without the need for water. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate. This tablet format is designed to allow administration of an oral solid dose form in the absence of water or fluid intake. Such tablets readily dissolve or disintegrate in the saliva/ oral cavity within less than one minute (within

Keywords: Mouth dissolving tablets=MDT.