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Abstract

BILAYER TABLET: A REVIEW

Neha P. Singh*, G. Ganarajan and Preeti Kothiyal

ABSTRACT

Bilayer tablet is new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Bilayer tablets can be a primary option to avoid chemical incompatibilities between API by physical separation, and to enable the development of different drug release profiles (immediate release with extended release). article provides an overview of the state-of-the-art of bilayer tablet technology, highlighting the main benefits of this type of oral dosage forms while providing a description of current challenges and advances toward improving manufacturing practices and product quality. There is various application of the bilayer tablet it consist of monolithic partially coated or multilayered matrices. This review explains fundamentals of bilayer tablet system along with its fabrication techniques, different approaches, characterization, challenges in Bilayer tablet manufacturing, Quality & GMP requirements, for their production and recent developments in the field of bilayer technology.

Keywords: immediate release with extended release.


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