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Abstract

MICROWAVE SYNTHESIS OF NEW PYRAZOLINES DERIVATIVES AND THEIR BIOLOGICAL ACTIVITY

Laxmi Lal Dangi, *Dr. G. P. Singh and Dr. S. S Dulawat

ABSTRACT

Newly 1-(2,4-dinitrophenyl)-5-(3-phenoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazole (1a-1f) were synthesized by the reaction of substituted meta-phenoxychalcones with 2,4-dinitrophenyl hydrazine (2,4-DNPH) in either formic acid or acetic acid in ethanol, respectively. The structures of the newly synthesized compounds were established on the basis of IR, 1H NMR, mass spectral data and elemental analyses. The compounds were evaluated for their antibacterial.

Keywords: Microwave, Chalcones, Pyrazoline, Antibacterial.


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