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Abstract

A REVIEW ON ANALYTICAL METHODS FOR DETERMINATION OF CEPHALOSPORINS AND OXAZOLIDINONES BULK AND IN DIFFERENT DOSAGE FORMS

Kinjal A. Patel, Dr. Jignesh S. Shah*, Dr. Dilip G. Maheshwari

ABSTRACT

Cephalosporins and oxazolidinones are very effectively used as anti-microbials. They very potent in nature and used in complex infections cephalosporins work by interfering with cell wall synthesis while oxazolidinone act as potent anti bacterial. They used to treat pneumonia, strep throat, staph infections, tonsillitis, bronchitis, otitis media, various types of skin infections, gonorrhea; urinary tract infections cephalosporin antibiotics are also commonly used for surgical prophylaxis. They are generally administered as tablets as well as through intravenously. This review entails different methods developed for determination of the combination of cephalosporins and oxazolidinones like UV-spectroscopy and liquid chromatography.

Keywords: Cephalosporins, Oxazolidinones, UV-Spectroscopy, High Performance Liquid Chromatography (HPLC).


[Full Text Article]

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