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Abstract

A REVIEW ON SYNTHETIC APPROACHES OF PYRAZOLINE DERIVATIVES

Sarita A. Shinkar, Vaybhav J. Shetty and Deepali M. Jagdale*

ABSTRACT

Pyrazolines as a scaffold have come into prominence in the field of medicinal chemistry this is due to the fact that the scaffold has a rich and diverse range of activities, another important reason for the popularity of this scaffold is its ease of synthesis. Various analogues of the scaffold show different activity and have different route of synthesis. The mode of synthesis of these various analogues has not been dealt thoroughly in the literature. This article mainly focuses on the synthesis of different Pyrazoline derivatives. Thus this review will be helpful for all researchers who are attempting to synthesize various derivatives of Pyrazoline in their research work.

Keywords: Synthesis, Pyrazoline, chalcone, phenyl hydrazine, Claisen-Schmidt reaction.


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