Abstract

THE EFFECT OF ETHANOL EXTRACT FROM LEAVES OF COFFE PARASITE (SCURRULA FERRUGINEA (JACK) DANSER) ON THE LEVEL OF CHOLESTEROL WHITE MALE MICE

Dillasamola D.*, Dharma S. and Dianasari F.

ABSTRACT

The effect of ethanol extract from coffee parasite leaves (Scurrula ferruginea (Jack) Danser) on the level of cholesterol has been investigated to white male mice enzimatically using Nesco Multy Check. This study was conducted experimentally using 4 groups of mice, one group as negative control group and the rest as groups of treatment. Optimization of cholesterol was conducted by giving a quail’s yolk about 1% BW for 7 days. Samples were given orally in suspension with the doses 100, 200 and 400 mg/kg BW respectively for 21 days and the cholesterol level was determined at the 7th, 14th, and 21st day. Cholesterol data were analyzed by two-way ANOVA. The result showed that correlation of the ethanol extract of parasite coffee leaves at various doses with the length of administration was not significantly different (p> 0.05). After being followed by Duncan’s Multiple Range Test, we did not find significant difference between control and treatment groups.

Keywords: (Scurrula ferruginea (Jack) Danser), Ethanol Extract, Cholesterol.