Abstract

IMMEDIATE RELEASE TABLETS: A SURROGATE FOR ORAL DRUG DELIVERY

Komal*, Bhandari Neeraj, Jagrity Thakur

ABSTRACT

Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however in many cases immediate onset of action is required than conventional therapy. To overcome these drawbacks, immediate release pharmaceutical dosage form has emerged as alternative oral dosage forms. There are novel types of dosage forms that act very quickly after administration. The basic approach used in development tablets is the use of super disintegrants like Cross linked carboxymelhyl cellulose (Croscarmelose), Sodium starch glycolate (Primogel, Explotab), Polyvinylpyrrolidone (Polyplasdone) etc. which provide instantaneous disintegration of tablet after administration.

Keywords: Immediate release, Superdisintegrants. Direct compression, Wet Granulation.