Abstract

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NICKEL (II), TITANIUM (IV) COMPLEXES

T.S.Sribharathi*, K.Gayathri and A.Ayyammal

ABSTRACT

Titanium (IV) and Nickel (II) complex of N (benzylidene) 1- amino-2- naphthol-4-sulphonic acid was synthesized from the ligand N (benzylidene) 1- amino-2- naphthol-4-sulphonic acid with Titanium (IV) dioxide and Nickel (II) Chloride under proper condition. Freshly prepared ligand N (benzylidene)1- amino-2- naphthol-4-sulphonic Acid (3.73g, 0.02 mol) Titanium dioxide (3.99g, 0.01 mol), Nickel Chloride (3.99g, 0.01 mol), ethanol (20 ml), 2drops of acetic acid were refluxed in a steam bath for about six hours using water condenser. A light violet precipitate of Titanium (IV) and Nickel (II) complex of N (benzylidene) 1- amino-2- naphthol-4-sulphonic acid was obtained.The disc diffusion method was used to screen the antimicrobial activity. Presence of phenyl ring in a compound are excited to show aromatic (C-H) stretch in the region 1861-1920 cm-1. The appearance of two bands with value 2044 cm-1 is due to stretching vibration. Analysis of the complex reveals that all the ligands showed greater activity against E. faecalis and S.typhi, complexes showed its greater activity against Lactobacillus and S.typhi.

Keywords: Nickel (II) and Titanium (IV) Complexes.