Abstract

THE STUDY OF SUBSTITUTED INDOLE: SYNTHESIS, ANTIBACTERIAL AND ANTIFUNGAL EVALUATION OF 3- (2', 3'-EPOXYPROPYLOXIMINO)-1-BENZOYL INDOLE-2-ONE. 3, 3-(3'-SUBSTITUTED PHENYL-2'-HYDROXY PROPYLOXIMINO)-1-BENZOYL INDOLE-2-ONE

Ravindra Kumar*

ABSTRACT

Several 3-(2',3'-Epoxypropyloximino)-1-benzoyl indole-2-one 3, 3-(3'-Substituted phenyl-2'-hydroxy propyloximino)-1-benzoyl indole-2-one have been synthesized by using conventional synthetic strategy. All the synthesized compounds have been characterized by elemental (C,H,N) and spectral (I.R., 1H- NMR, Mass) analysis. Furthermore, synthesized compounds were screened for their antibacterial as well as antifungal activities. Screened derivatives explored mild to moderate antibacterial and antifungal inhibition.

Keywords: indole-2-one, antibacterial and antifungal activities.