Abstract

SCHIZOPHRENIA: PSYCHO-SOCIAL DEMOGRAPHIC PROFILE AND DRUG UTILIZATION STUDY OF ANTI-PSYCHOTICS AT A GOVERNMENT MEDICAL TEACHING HOSPITAL

Neeli Uma Jyothi, Pamidi Pradeep*, Madapati Vinod Kumar, Kanneganti Sandeep, Panugandla Ramadasu, Nadendla Rama Rao

ABSTRACT

Objective: To assess the drug utilization and prescribing pattern of antipsychotic agents in Schizophrenia patients with regard to drug, drug class, ATC coding, combination therapy and sociodemographic details. Methodology: A prospective observational study, for 6 months in the psychiatry department of a tertiary care hospital. Ethical clearance was obtained prior to the study. Data was collected by using a patient data collection form and the antipsychotic drug use was recorded. Results:186 patient’s data was recorded and analyzed statistically for the pattern of use of antipsychotics. olanzapine(27.98%) was found to be most prescribed followed by risperidone(20.98%), haloperidol (6.45%) and chlorpromazine (8.60%). Total no. of drugs prescribed for 186 patients is 428, mean of the drugs prescribed per prescription is 2.30, total no. of antipsychotic drugs prescribed is 218, average number of antipsychotic drugs per prescription is 1.17.Conclusion: Atypical antipsychotics(olanzapine, risperidone) were the most prescribed compared to the typical antipsychotics(haloperidol, chlorpromazine). Most of the drugs were prescribed by generic names, only few drugs was prescribed by their brand names. and no polypharmacy was seen.

Keywords: Schizophrenia, Drug utilization study, antipsychotic agents, Prescribing Pattern.