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Abstract

DEVELOPMENT AND VALIDATION OF REVERSE PHASE HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF MONTELUKAST SODIUM AND EBASTINE IN ITS TABLET DOSAGE FORM

Dr. Hepcy Kalarani D*, Shaanthi A, Dr. Venkatesh P, Lakshman Kumar D, Dr. Purushothaman M

ABSTRACT

Development and validation of reverse phase HPLC method for the simultaneous estimation of montelukast and ebastine in its tablet dosage form. The reverse phase HPLC includes stationary phase is non-polar hydrophobic packing with octyl (or) octa decyl functional group bonded to silica gel and mobile phase is polar solvent. Montelukast is used regularly to prevent the wheezing and anti-asthma. Ebastine is an anti histamines.

Keywords: Reversephase, montelukast, ebastine, stationaryphase, non-polar, hydrophobic, octyl, octa decyl, mobile phase, wheezing, anti-ashtma.


[Full Text Article]

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