Abstract

EXPERIENCE OF AZELAIC ACID USE IN ACNE TREATMENT

Khairutdinov VR*, Belousova IE, Statsenco AV, Samtsov AV

ABSTRACT

Acne treatment is one of the important problems in modern dermatology. The goal of the study was to evaluate clinical efficacy and safety of the drug «Azelik» (15% azelaic acid gel) in the treatment of patients with papulopustular acne mild to moderate in severity. Material and Methods: an open comparative 8-week study, which enrolled 75 patients. In order to assess the safety and efficacy of the therapy, complete blood count, blood chemistry panel, and urinalyses were performed, along with evaluation of dermatological status, measurement of pH value, levels of skin hydration and sebum production, and assessment of Dermatology Life Quality Index (DLQI) in the study participants. Results: 82% of the patients who were receiving treatment with Azelik gel showed clinical recovery or significant clinical improvement. Conclusions: The results of the study indicate the high level of safety and tolerability of the Azelik gel. Clinical results obtained during the study have proven the therapeutic efficacy of the Azelik gel in the treatment of papulopustular acne mild to moderate in severity.

Keywords: papules, pustular acne, topical therapy, azelaic acid, «Azelik» gel.