Abstract

SCREENING OF PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF MEDICINAL PLANT EXTRACTS

V.Rama*, G. Venkat Raji Reddy, R.Vijay Kumar and M. Krishna Reddy

ABSTRACT

In the recent past there has been a tremendous increase in the use of plant based health products in developing as well as developed countries resulting in an exponential growth of herbal products globally. An upward trend has been observed in the research on herbal products. Herbal medicines have a strong traditional or conceptual base and the potential to be useful as drugs in terms of safety and effectiveness leads for treating different diseases. The phytochemical analysis revealed the present study; the Streblus asper aqueous leaf extract (SAALE) showed Tannins, Flavonoids, Saponins and Phenols where as the methanol extract (SAMLE) of the plant showed Tannins, Phenols, Flavonoids, Saponins, Steroids. Other extracts from the toluene expressed Flavonoids, Phenols, Steroids and Ethanol extract showed Flavonoids, Phenols, and Steroids. The DPPH free radicals were inhibited by SAALE & SAMLE. The inhibition of the free radicals was increased, as the concentrations of the extracts increased. The effect of inhibition of SAMLE was greater than to the effect of the SAALE. The results of the extracts were compared to the standard drug Ascorbic acid. The IC50 (Inhibited concentration) is the value that inhibition the DPPH for 50% by the extract and the standard drug. The IC50 values of the Ascorbic acid, SAMLE and SAALE were 51.26μg/ml, 57.97μg/ml and 69.6μg/ml respectively. The results indicate that both the extracts clearly have strong antioxidant effects.

Keywords: Tannins, Flavonoids, Saponins, Phenols, antioxidant activity.