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Ashok Kumar. D*, M. Venkata Subbaiah and M. Purushothaman





Adverse drug reactions (ADRs) are considered as one among the leading causes of morbidity and mortality. The aim of the study is to conduct the surveillance of adverse drug reaction and minimize them for better patient care. A Prospective Adverse Drug Reaction Reporting Method was conducted in the General Medicine Department of a tertiary care teaching hospital for 6 months from September 2014 to February 2015 to detect and suspect ADRs and to analyse the causality, severity and preventability using appropriate validated scales. ADR alert card was prepared and given to patients. Therapeutic guidelines were prepared and given to the relevant departments. A total no. of 184 patients were followed among them males were (39.13%) and females were (60.87%). 8.6% were from paediatrics department, 78.4%patients were from general medicine and 13.0% patients were from geriatrics. A total of 128 ADRS from in-patient department and 56 ADRS from out- patient department were reported & the highest no. of ADRs was found with antibiotics. Gastro intestinal system 76(41.30%) was the most commonly affected organ. 110(59.78%) adverse drug reactions were due to predisposing factors. 94.56% ADRs required medical intervention to prevent permanent impairment or damage .In majority of the ADRs the suspected drug was withdrawn 62(33.69%) and 74(40.21%) required symptomatic treatment. 79 ADRs (42.93%) recovered after the management. Maximum reporting of the ADRs was done by the clinical pharmacist 126(68.47%). This study helped in a better monitoring of the therapy given to the patient, helps in the drug safety and efficacy.

Keywords: Adverse Drug reactions, Clinical Pharmacist, Patient Safety, Pharm. D.

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