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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

STABILITY-INDICATING RP-HPLC METHOD DEVELOPMENT FOR THE ESTIMATION OF PANTOPRAZOLE SODIUM IN TABLET DOSAGE FORM

Faraat Ali*, Dr. G. N. Singh, Dr. P. L. Sahu, Anuj Prakash, Manisha Trivedi, Tanzeel A. Khan

ABSTRACT

The aim of the present study is to develop a simple, sensitive, rapid, accurate and precise reverse phase high performance liquid chromatographic (RP-HPLC) method for the estimation of Pantoprazole sodium in bulk and pharmaceutical dosage forms. Analytical method was developed by using Waters X-Bridge Shield C-18 (4.6×150 mm, 5μm) column; mobile phase consisting of ACN and ammonium bicarbonate phosphate buffer at pH 9.0; the flow rate of 1.0 ml/min and detection wavelength 214nm and eluted at 4.766 min. The method was found to be simple, accurate, economical, Precise and reproducible. There was no interference of any degradants and excipient in the determination of drugs in marketed formulation. So the method can be successfully applied for routine analysis.

Keywords: Pantoprazole, Acetonitrile, HPLC, Development.

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