WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

FORMULATION AND EVALUATION OF SALBUTAMOL TRANSDERMAL MEMBRANES USING POLYETHYLENE GLYCOL AS PERMEATION ENHANCER

Sam Johnson Udaya Chander J.*, Akelesh T, Ardra A, Misariya Sidheek T, Noufal VP, Venkatanarayanan R

ABSTRACT

Salbutamol is a beta2-adrenergic receptor agonist, which is used as an anti-asthmatic drug. The objective of the present study is to incorporate Salbutamol in the transdermal drug delivery system using polyethylene glycol as permeation enhancer and as plasticizer. The placebo and medicated films were evaluated for physiochemical properties and the medicated films were evaluated for uniformity of drug content, area variation and percent cumulative drug release. The in-vitro release study was performed using Franz diffusion cell. The patches were found to be thin and smooth and the permeation followed zero order kinetics. The release pattern of the drug extends up to 12 hours with 79% cumulative drug release, which entails this product with sustained drug release characteristic and this can minimize the frequent administration of conventional salbutamol dosage form. The medicated films also went through primary skin irritation test and the results showed that the films were non-irritant.

Keywords: Salbutamol, HPMC, polyethylene glycol, Franz diffusion cell.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More