Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

ANTIBACTERIAL AND ANTIFUNGAL STUDIES OF 5- ISOPROPOXYCARBONYL-4-ARYL-6-METHYL-3, 4-DIHYDROPYRIMIDIN-2(1H)-THIONES

S. Chitra* and D.Devanathan

ABSTRACT

Seven 5-isopropoxycarbonyl-4-aryl- -6-methyl-3,4-dihydropyrimidin-2(1H)-ones 4ag are screened for their antibacterial activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi and antifungal activity against Candida albicans, Aspergillus flavus, Rhizopus and Mucor. Ciprofloxacin is used for the standard for antibacterial and Amphotericin B is used for the standard for antifungal studies. Compounds 4b, 4c, 4f and 4g exhibited excellent in vitro antibacterial activity against all the tested organisms. Whereas the same set of compounds exerted potent in vitro antifungal activity against Candida albicans, Aspergillus flavus and Rhizopus.

Keywords: Antibacterial activity, antifungal activity, Dihydropyrimidinones, Ciprofloxacin, Amphotericin B.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More