Abstract

ORALLY DISINTEGRATING TABLETS (ODTs)- A COMPREHENSIVE REVIEW

Nagasamy Venkatesh D,*, Kiran H.C, Shashikumar. S, Jenisha Karmacharya, Veeramachaneni  Krishna Priya, Kosaraju Bhavitha and Ayush Shrestha

ABSTRACT

Oral drug delivery system is considered as the safest, economical and most convenient drug delivery method having highest patient compliance. Patience compliance has always been a major factor in developing a drug delivery system. This has attracted scientists over the world to develop various fancy oral drug delivery systems. Orally disintegrating tablets, by overcoming previously encountered problems of drug administration has gained remarkable market acceptability. Orally disintegrating tablets (ODTs) are most preferred and accepted solid dosage forms. They disintegrate in mouth within a short period of time and are useful for populations having difficulty in swallowing. This article aims at providing a brief review on requirements for orally disintegrating tablets, their advantages and disadvantages, formulation aspects, various conventional and patented technologies for its manufacture, methods of evaluation and its applications.

Keywords: ODTs, conventional technologies, patented technologies, superdisintegrants.