Abstract

SYNTHESIS AND BIOLOGICAL EVALUATION OF BENZIMIDAZOLE DERIVATIVES

J. Kamal Chandra*, Dr.R.Srinivasan, G.Vasavi, P.Vijaya Lakshmi, S.Swathi, K.Latarose, M.Radhika, N.Swathi

ABSTRACT

Heterocyclic compounds are those cyclic compounds whose ring contain besides carbon, one or more atoms of other elements. Benzimidazoles are regarded as a promising class of bioactive heterocyclic compounds that exhibit a range of biological activities like anti-microbial, anti-viral, anti-diabetic, anticancer activity.In the present study benzimidazole derivatives are synthesized by using Ophenylene diamine and aminoacids like Glycine,Tyrosine and Cysteine.The synthesized compounds structures are determined by using IR and Mass spectra.The benzimidazole derivatives have been evaluated for anti-microbial and anthelminthic activities.

Keywords: Benzimidazole, O-Phenylene diamine, Glycine, Tyrosine, Cysteine and Anti microbial activity.