Abstract

INVESTIGATION OF IN-VITRO ANTHELMENTIC ACTIVITY OF TRIDAX PROCUMBENS

R. R. Dhangar, S. M. Nikumbha*, M. M. Mane, H. P. Suryawanshi, S. P. Pawar

ABSTRACT

The aqueous and ethanolic extract of Tridax procumbens, linn (Asteraceae) was evaluated for Anthelmintic activity. The dried powder of Tridax procumbens(leaves) containing chemical constituent procumbent was extracted and the activity was studied. Both aqueous and ethanolic extract collected were tested for Anthelmintic activity against Indian adult earthworm Pheritima posthuma(Annelida) and recorded the time taken for induction of paralysis and death. Various concentration ( 50 mg/ml and 100mg/ml) of aqueous and ethanol were evaluated in the bioassay involving determination of time of paralysis (P) and time of death (D)of the worms. Albendazole suspension (25mg/ml) was used as standard Anthelmintic drug and Normal saline solution was used as control. The comparative results of present study indicated that the aqueous and ethanolic extract of Tridax procumbens, linn shows significantly dose depending pharmacological activity on the earthworms.

Keywords: Anthelmintic activity, Pheritima posthuma, Tridax procumbens.