Abstract

A COMPARATIVE STUDY OF EFFICACY OF TWO DIFFERENT SAMPLES OF AMRITA GUGGULU IN THE MANAGEMENT OF VATARAKTA

Usha Sharma, Krishna Kumar Sharma and Mohita Bohra

ABSTRACT

Vata-rakta is the major example of Vata Vyadhi, caused due to Avarana pathology. The literature enlists a number of Guggulu Prayogas in the management of Vata-rakta. In Chakradutta, Vatavyadhi Rogaadhikaar, Chapter 23, two types of Amrita Guggulu, Pratham and Dwitiya, here named Sample I and Sample II are described. This is a single-blind comparative clinical study with a pretest and post-test design, wherein a minimum of 60 patients of both sex, suffering from Vata-rakta, in an age limit of 20 to 60 years, were selected and randomly categorized into two groups. The 30 patients of group A were treated with oral administration of Tab Amrita Guggulu Sample I 500 mg thrice a day and the group B patients with Tab Amrita Guggulu Sample II of the same dose pattern with Anupana of Amritaadi Kashaya 72 ml with each dose. The therapeutic effect of the treatment was assessed in both the groups based on specific subjective and objective parameters. The results obtained were analyzed statistically in both the groups. In both the groups, statistically significant improvement was observed in all the criteria of assessment. The outcome of the study revealed a better therapeutic efficacy of Amrita Guggulu Sample II than Amrita Guggulu Sample I in Vata-rakta. The use of Amrita Guggulu Sample II as Shamana Aushadha was a perfect selection in the management of Vata-rakta. As a preliminary study, it has paved the further scope of study with bigger sample size in management of Vata-rakta.

Keywords: Gout, Hyperuricemia, Serum Uric Acid, Tenderness, Vata-rakta.