WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

MICHELIA CHAMPACA: A USEFUL REMEDY FOR MAST CELL STABILIZATION, ANTIALLERGIC AND ANAPHYLACTIC ACTIVITY IN MANAGEMENT OF ASTHMA

Dr. Anupama A. Suralkar*, Tayade G.V. and Dose R. S.

ABSTRACT

The anti-allergic, anti-anaphylactic and mast cell stabilizing activity of ethanolic extract of Michelia champaca (MC) was evaluated pharmacologically by using milk induced leukocytosis and eosinophilia in mice, compound 48/80 induced mast cell degranulation in rats and egg albumin induced passive paw anaphylaxis in rats. In the milk induced eosinophilia and leukocytosis, MC showed significant inhibition of the total number of eosinophils and leukocyte count in mice; in the compound 48/80 induced mast cell degranulation MC showed significant protection of mast cells in rats; and in passive paw anaphylaxis, MC showed significant reduction in the paw edema volume in rats. These results suggest that MC may prove to be a potential therapeutic agent in management of asthma which may be due to anti-stress, mast cell stabilizing and anti-inflammatory activity.

Keywords: Michelia champaca, milk, compound 48/80, anaphylaxis.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More