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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL CHALCONES AND PYRAZOLINE DERIVATIVES FROM 1-(3-CHLOROPHENYL) ETHANONE

G. Eswara Rao *, P. Srinivasa Babu, J Sambrajyam, N. Sresta, Md. Shaheem Sultana, R. Lakshmi Durga, K. Srikanth

ABSTRACT

Novel chalcones were synthesized by condensing 1-(3-chlorophenyl) ethanone with aromatic aldehydes derivatives in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen - Schmidt condensation. The synthesized chalcones compounds were reacted with hydrazine sulphate upon cyclisation gives pyrazoline derivatives. All these compounds were characterized by means of their IR, 1H NMR spectroscopic data and microanalyses. The antimicrobial activity of these compounds was evaluated by the cup plate method.

Keywords: Chalcones, Pyrazole, Synthesis, Antimicrobial activity

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