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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

DERIVATIVES OF 2-QUINOLONES: SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL EVALUATION

Dr. Sukhen Som*

ABSTRACT

The present investigation deals with the synthesis and antibacterial evaluation of a series of 2-quinolone derivatives. The structural analysis and characterizations for the analogues were performed by their IR, 1HNMR and Mass spectral studies. The compounds were evaluated for antibacterial activity by cup-plate method. Compounds 3h, 3i and 3j showed good activity against the bacterial strains compared to the standard drug. In view of the antibacterial studies performed it can be concluded that these derivatives can be utilized and investigated further for their optimum pharmacodynamic and pharmacokinetic properties.

Keywords: Acylation, m-toluidine, antibacterial activity.

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