Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • JULY 2021 Issue has been successfully launched on 1 July 2021.



*Shaik. Harun Rasheed1, N.Tirumooorthy2, Kundlik Girhepunje1.

1Department of Pharmaceutics, NIMS University, Jaipur, Rajasthan, India.
2Department of Pharmaceutics, Cheran College of Pharmacy, Coimbatore, Tamilnadu, India.
3Department of Pharmaceutics, Peoples University, Bhopal, Madhya Pradesh, India.


Ketoconazole is an antifungal drug useful in treatment of both dermatophytosis and systemic mycosis. However its oral administration is associated with number of demerits. The goal of the current investigation is to evaluate the transdermal potential of novel vesicular carrier, ethosomes, bearing ketoconazole an antifungal having limited transdermal permeation. ketoconazole loaded ethosomes were prepared, optimized and characterized for vesicular shape and surface morphology, vesicular size, size distribution, entrapment efficiency, vesicles skin interaction and stability. The ethosomal formulation (E9) having 3% phospholipids content and 40% ethanol showing the greatest entrapment (77.813.5%) and size range (1699.4 nm) was selected for further transdermal permeation studies. An optimum polydispersity index (0.1020.009) of ketoconazole loaded ethosomal formulation could better justify the homogeneous nature of the prepared ethosomal formulation Skin entrapment efficiency assessed by confocal laser scanning microscopy (CLSM) which revealed that enhanced permeation in the deeper layer of the skin (156 μm). Vesicle skin interaction study also showed that there was no interaction between the formulation and rat skin. Furthermore ethosomal delivery system could be considered for the treatment of number of dermal infections with better efficiency.

Keywords: Enhanced drug delivery, ethosomes, dermatophytosis, confocal laser scanning microscopy, systemic mycosis.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More