Abstract

PHYTOCHEMICAL SCREENING AND ANTHELMINTIC ACTIVITY DETERMINATION OF BOERHAAVIA DIFFUSA ROOTS HYDRO ALCOHOLIC EXTRACT

Dr. Fathima Nausheen Usman*, Dr. Atthapu Thirupathaiah, Dr. Madireddy Mamata

ABSTRACT

Boerhaavia diffusa roots are widely used in traditional medicine for the treatment of various disorders. The present study was carried out to evaluate the phytochemical constituents and anthelmintic activity of the hydroalcoholic extract of B. diffusa roots. Anthelmintic activity was assessed using Pheretima posthuma as the experimental worm model. Different concentrations of the extract (25, 50, and 100 mg/ml) were tested and compared with albendazole as the standard drug. The activity was evaluated by recording the paralysis and death times of worms. The results revealed significant dose-dependent anthelmintic activity, where higher concentrations produced faster paralysis and death. The presence of phenolic tannin, and flavonoid constituents may contribute to the observed activity. The study concludes that the hydroalcoholic extract of B. diffusa roots possesses promising anthelmintic potential and may be useful for further herbal drug development.

Keywords: Boerhaavia diffusa, Pheretima posthuma, anthelmintic activity, albendazole.