Abstract

A REVIEW ON CURCUMIN LOADED CHITOSAN-BASED HYDROGELS FOR ACNE TREATMENT FORMULATION PARAMETERS IMPACTING ANTI-MICROBIAL RELEASE AND EFFICACY

*Anil Kumar M. K., Dr. Vijaykumar Meti, Dr F. S. Dasankoppa

ABSTRACT

Despite significant progress in modern allopathic treatments and healthcare infrastructure in developing countries, about 60% of the global population still depends on plant-based remedies for managing illnesses. Furthermore, nearly 75% of people worldwide continue to practice traditional medicinal systems, such as Ayurveda and Unani. Mango ginger (Curcuma amada), a rhizomatous aromatic herb, is a member of the Zingiberaceae family and is widely recognized for its therapeutic potential.[1] The discovery of curcumin began around 200 years ago when Vogel and Pelletier revealed the successful separation of curcumin. This yellow pigment made from the rhizomes of Curcuma longa, often known as turmeric, is called curcumin.[2] Turmeric is obtained from Curcuma longa L., a perennial herbaceous species distinguished by its tuberous roots, yellow flowers, and broad leaves. This plant, a member of the Zingiberaceae family, predominantly grows in tropical regions.[3] Curcuma longa has long been utilized as a natural colorant, flavouring, and medicinal herb, particularly in Asian countries. Indian traditional medicine, culinary, and cosmetic items all make extensive use of it. Curcumin, the primary bioactive component, has a variety of pharmacological effects, including anti-inflammatory, antioxidant, chemopreventive, and possibly enhanced chemotherapeutic efficacy.[4] Since ancient times, humans have relied on herbs and natural products to treat a variety of ailments. The Indian subcontinent, known for its rich biodiversity, hosts numerous aromatic and medicinal plants. Prior to their adoption as primary therapeutic agents, it is crucial to rigorously evaluate and standardize Unani and Ayurvedic medicines to ensure their efficacy, safety, and quality. Across cultures, plant-based therapies remain integral to healthcare, with many countries allocating 40% to 50% of their health budgets to the development of new herbal drugs. Herbal medicines are generally perceived as beneficial to health with minimal risk of adverse effects.[5]

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