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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.485

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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Abstract

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF BISOPROLOL FUMARATE: A TECHNICAL REVIEW

Smruti B. Patel*, Henil D. Patel, Kriya R. Patel, Dhruv M. Patel, Zeel B. Patel, Dr. C. N. Patel, Dr. Khushbu Patel

ABSTRACT

Bisoprolol fumarate is a drug mainly used for the long-term treatment of high blood pressure. It works by reducing the heart rate and lowering the workload on the heart, which helps in controlling blood pressure with fewer breathing-related side effects. This review focuses on different analytical methods such as UV-Visible Spectroscopy, HPLC, and HPTLC used for estimation of Bisoprolol fumarate in bulk and pharmaceutical dosage forms. It also highlights the importance of method validation as per ICH guidelines to ensure the quality, safety, and effectiveness of the drug.

Keywords: Bisoprolol fumarate, Hypertension, RP HPLC, UV Spectroscopy, Method validation, Stability indicator.

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