Abstract

NAEGLERIA FOWLERI INFECTION: CURRENT INSIGHTS INTO EPIDEMIOLOGY, DIAGNOSIS, AND TREATMENT - A REVIEW

*P. Ujwala Rama Chandra, M. Jyothsna Sri, M. Venkata Naga Prasad, N. Jyoshna, M. Susmitha, N. Kavya Pranathi, N. Sri Vani

ABSTRACT

Naegleria fowleri is heat- loving amoeba that causes primary amoebic meningoencephalitis (PAM), a rare but deadly brain infection. It enters the body through the nose when people swim or dive in warm freshwater and also reaches the brain, causing severe inflammation. PAM has a death rate of over 95, substantially due to late opinion and limited treatment success. Tests like microscopy and PCR can descry it, but frequently too late. medicines similar as amphotericin B and miltefosine are used, but survival is rare. The stylish way to help PAM is by raising public mindfulness and perfecting water safety.

Keywords: Naegleria fowleri, Primary amoebic meningoencephalitis (PAM), Miltefosine, Drug repurposing, Water bone pathogen, Public health awareness.