Abstract

A REVIEW ON TRANSDERMAL DRUG DELIVERY SYSTEM

Sonali Patidar*, Shweta Shitole

ABSTRACT

Transdermal drug delivery systems have several advantages over traditional delivery systems. It has both local and systemic therapeutic properties. Controlled plasma drug levels, reduced dosing frequency, and avoidance of hepatic first-pass metabolism are just a few of these systems’ advantages. The skin is the body’s largest organ and serves as a site of administration for various medications. Transdermal drug delivery systems [TDDS] provide prolonged therapeutic effects, reduced side effects, enhanced bioavailability, improved patient compliance, and easy termination of drug therapy. TDDS finds applications not only in pharmaceuticals but also in the skincare and cosmetics industries. This review article provides a comprehensive overview of TDDS, highlighting its advantages over conventional dosage forms, addressing limitations, discussing the components of transdermal patches, exploring different types of transdermal patches, describing methods of preparation, and outlining the ideal requirements for TDDS. Furthermore, it delves into regulatory considerations, physicochemical methods of evaluation, therapeutic applications, and recent advancements in the field of transdermal drug delivery systems."

Keywords: Tdds; Transdermal Patch; Permeation Enhancer; Partition Coefficients; Iontophoresis.