Abstract

“HERBAL AND BOTANICAL AGENTS IN THE TREATMENT OF MELASMA: A REVIEW OF INGREDIENTS, DEVELOPMENT & EVALUATION”

*Yogita Charde, Vijay Chaudhari

ABSTRACT

Melasma is a chronic skin pigmentation disorder characterized by symmetrical brownish or grayish patches, primarily on the face, and it predominantly affects women. The condition is influenced by factors such as hormonal changes, genetic predisposition, and sun exposure, making it both persistent and challenging to treat. Conventional treatments like hydroquinone, chemical peels, and laser therapies can provide temporary improvement, but they often come with side effects such as skin irritation, redness, or recurrence of pigmentation after stopping the treatment. In recent years, herbal and botanical agents have gained attention as safer alternatives due to their natural skin-lightening properties and minimal adverse effects. Several plant-derived compounds show promise in managing melasma because of their antioxidant, anti- inflammatory, and tyrosinase inhibitory activities. For example, Aloe vera soothes and hydrates the skin, Licorice (Glycyrrhiza glabra) reduces melanin production, Turmeric (Curcuma longa)helps control pigmentation through its anti-inflammatory and antioxidant effects, while Green tea (Camellia sinensis) and Mulberry (Morus alba) inhibit melanin formation and protect the skin from oxidative stress. Integrating these herbal remedies with conventional therapies may offer a more balanced, safer, and long-term approach to controlling melasma, potentially reducing side effects while improving overall skin health.

Keywords: Melasma, Hyperpigmentation, Facial pigmentation, Skin disorder, Women’s skin health, Herbal treatment, Botanical agents, Aloe vera, Liquorice (Glycyrrhiza glabra), Turmeric (Curcuma longa), Green tea (Camellia sinensis), Mulberry (Morus alba), Tyrosinase