Abstract

NANOTECHNOLOGY IN TB: TINY SOLUTIONS FOR A GLOBAL EPIDEMIC

*Sudeshna Rani Dutta, Anupama Katoch

ABSTRACT

Tuberculosis (TB) is one of the most dangerous infectious diseases and continues to be a major public health challenge globally. The treatment of TB is complex because it involves taking numerous medications over an extended period, adhering to strict routines, and managing various side effects. Many individuals struggle to maintain their treatment regimen, which can result in the development of drug-resistant TB, including multidrug-resistant (MDR) and extensively drug-resistant (XDR) forms. These resistant strains pose a significant risk because there are limited effective treatments available, making TB more difficult to control.This is where nanotechnology offers a promising solution. Nanotechnology employs extremely small particles known asnanoparticles to enhance both the detection of TB bacteria and the delivery of medications within the body. Recent studies have shown that using nanoparticles improves the effectiveness of TB drug delivery, requiring smaller doses and reducing side effects. This makes it easier for patients to adhere to their treatment plan and recover more quickly.

Keywords: Drug delivery systems, Extensive drug-resistant tuberculosis, Multidrug- resistant tuberculosis, Nanoparticles, Therapeutics, Tuberculosis.