Abstract

ANTIFERTILITY EFFICACY SEMICARPOUS ANACARDIUM SEED ON FEMALE ALBINO RATS

Vandana Deshmukh, Varsha Zade*

ABSTRACT

The present study was carried out in female albino rat to explore the abortifacient activity of the Semicarpous anacardium seed. Pregnant rats weighing 170-220 gm were randomize in to groups of six animals each. Rats were laprotomised on 10th day of pregnancy and the two horns of auteri were examined to determine the implantation sites. Aqueous, alcoholic and petrolium ether extract Semicarpous anacardium exhibited significant abortificient activity (100%). The extract shows estrogenic activity and prolonged the estrous cycle in experimental animal. The extract of Semicarpous anacardium decreased the ovarian and uterine weight, while a non significant increase in the body weight was seen. There was a slight decrease in the serum estrogen and an increase in serum progesterone level, while the LH and FSH were found to be significantly reduced. The phytochemical screening of the seeds of Semicarpous anacardium revealed the presence of flavonoids, simple phenolics, alkaloids, steroids and saponins.

Keywords: Antifertility Activity, Estrous Cycle, Semicarpous anacardium, Female Albino Rats, Estrogenic.