Abstract

FORMULATION OF DIABETES HERBAL TABLET

*Vaishnavi Dattatray Changade, Vaishnavi Gawande, Vaishnavi Shipkule, Sakshi Shinde, Sakshi Ghuikar, Dnyaneshwari Sultane, Miss Sanika Wankhade, Miss. Gayatri Ingale, Mr. Pavan Satav

ABSTRACT

Medicinal plants have curative properties due to the presence of various complex chemical substance of different composition, which are found as secondary plant metabolites in one or more parts of these plants. Ipomoea digitata Linn. Convolvulus is a annual extensive perennial climber with large ovoid and tuberous roots herb indigenous to India and widely used in the treatments of hypolipodemic, hypoglycemic, for debility, to increase secretion of milk, to increases milk, poor digestion, tuberculosis, enlarged liver etc. It was also found to have alterative, aphrodisinc, cholagogue, demulcent, diuretic, rejuvenative actions. The present paper deals with formulation and evaluation of anti-diabetic activity of tablets prepared from aqueous extract of the selected plant. A solid pharmaceutical dosage formulation using a novel dry plant extract (tuberous roots) usingvarious excipients viz., carbopol, ethylcellulose, MCC, dibasic calcium phosphate and PEG4000 by direct compression was reported to be statically significant as anti-diabetic activity. The present communication also deals with the evaluation of formulated tablets (weight variation, friability, hardness and disintegration time). Medicinal plants play a very intportant role within the development of potent therapeutic agents. Nowadays estimate that concerning 80% of individuals in developing countries still relays on ancient drugs based mostly on species of plants and animals for his or her primary health care. Flavoring medication is use of therapeutic herbs to prevent and treat diseases and ailments or to support health and healing. The World Health Organization (WHO) estimates that 80% of the population of some Asian and African countries presently use flavored medication for a few side of primary health care. Prescription drugs are prohibitively dearly-won for many of the world’s population, half whom lived on less than $2 U.S. per day in 2002. One of the most common non-communicable diseases worldwide. India faces several challenges in diabetes management, including a rising prevalence in urban and rural areas, lack of disease awareness among the public, limited health care facilities, high cost of treatment, suboptimal glycaemic control and rising prevalence of diabetic complications. Insulin therapy for diabetes is most commonly delivered via subcutaneous injections, up to four times a day.

Keywords: Diabetes, Anti-inflammatory, Antipyretic, Analgesic, Herbal Tablet, Arthritis, Nyctanthesarbor- tristis.