Abstract

NANOPARTICLES- TARGETED DRUG DELIVERY IN BREAST CANCER – A REVIEW

Sulochana Dutta*, Piyush Kumar Shaw, Amitder Nath Chatterjee, Lokesh Kumar Mahato

ABSTRACT

Second only to lung cancer in terms of mortality, breast cancer is the most frequent cancer among women worldwide. Cancer, especially breast cancer, is typically treated with chemotherapy or radiation therapy, which are the current standard approaches for cancer therapy. Because chemotherapy and radiation damage healthy tissue and organs, they are both ineffective in treating breast cancer. Numerous nanoparticles that have the ability to specifically target tumor cells without endangering healthy cells or organs have recently been created and produced. Therefore, tailored drug delivery systems mediated by nanoparticles have become a promising therapy option for breast cancer. Nanoparticles have several special qualities that make them appealing for cancer treatment, in addition to their capacity to selectively target tumor cells and minimize side effects. These qualitiesinclude low toxicity, good compatibility, ease of manufacturing, and high stability. The availability of nanoparticles may be restricted by their high manufacturing costs. Here, we provide a comprehensive review of the most recent therapeutic research on several drug delivery systems mediated by nanoparticles as alternatives to conventional breast cancer treatment methods. In addition to providing guidance for future targeted drug delivery research aimed at creating an efficient treatment for breast cancer, it will highlight the significance of drug delivery systems mediated by nanoparticles.

Keywords: Breast Cancer, Drug Delivery, Nanoparticles, Therapy.