Abstract

A REVIEW ON PHARMACEUTICAL GEL

Shivam*, Shiv Kumar Chaudhari, Aman Verma, Aman, Jai Singh, Kumar Kartik Tripathi, Priyanka Gupta, Yadav Pooja Ramesh, Janvi Verma, Deepika Choudhary, Sandhya, Sarthak Jaiswal

ABSTRACT

The main intention of writing this review was to include the recent literature and specially focusing area of development in topical preparation and basic concept of topical drug delivery systems. Topical drug delivery has advantages such as applying the drug directly into skin and it also provides prolonged action on the specific site. There is different topical used formulation among the semisolid dosage forms gel formulations are becoming pre-eminent. Gels are colloids that are 99% liquid by mass, which is immobilized by surface tension among it and a macromolecules system of fibers constructed from a less amount of gelatinous substances present. The nature of solvent used categorizes gel into mainly two basic types ie, organogold andhydrogel. This review includes fundamental advantages of gel formulation above other semisolid formulation and other aspects like limitation, classification, formulation, mechanism involved and factors affecting gel formulation. A gel is a network of cross-linked polymers that expand in a liquid media. Gels are homogenous, semisolid preparations that typically consist of one or more medicament solutions or dispersions in appropriate hydrophilic or hydrophobic bases. Clinical research suggests that topical gels are the safest and most effective treatment choice for skin-related disorders, and that they are used topically to lessen associated adverse effects when compared to other traditional dose forms. The purpose of this article is to discuss the concepts and recent advancements in topical gels, such as classification, techniques of manufacture, characteristics, evaluation factors, and applications.

Keywords: Pharmaceutical gels; Terminologies; Characteristics; Classification; Preparation; Evaluation of Gels.